[INSERT YOUR CHILD'S NAME] Story

[INSERT YOUR CHILD'S STORY BELOW]

Please use this space to tell us a little about your child and the importance of a cure for GRI Disorder. 

Suggested word count is 250-450 words.

We have hope and we are grateful for your support in our journey to a cure.

Please Help Our Kids

GRI families like ours need your help to find treatments and cures for our kids.

Over the past few months, research teams from around the world have requested millions of dollars from CureGRIN to fund their research. 

Sadly, they don’t get enough money from governments and universities to develop life-changing medicines for our kids. They’re ready to test drugs and gene therapies, but they can’t do it without us.

The more money we raise in during Count Me In, the more of the following projects we can fund:

• Study to determine if patient blood can be used to diagnose GRI and measure if treatments are working.
• Study of non-neurological symptoms of GRI Disorder using Zebrafish
• Study to develop a predictive model to more quickly determine which GRI variants are pathogenic and which are loss vs. gain of function
• Several studies to test drugs on GRIN and GRIA cell and animal models
• Several studies to try rescuing GRI animal models through gene therapy or gene editing

What is GRI Disorder?

GRI Disorders are a set of rare genetic diseases affecting the brain. 

Symptoms include moderate to profound intellectual disability, epilepsy, dystonia, and gross and fine motor impairment, as well as sleep, vision and digestion challenges. While there are drugs that can help alleviate symptoms for some children, there are no approved treatments or cures for GRI Disorder itself.

Patients with GRI Disorder have a variant in one of the GRIN, GRIA, GRIK or GRID genes. These include GRIA1, GRIA2, GRIA3, GRIA4, GRIK2, GRIN1, GRIN2A, GRIN2B and GRIN2D.

Can we count on your support?